We see that mice that undergo caloric restriction show a lower

We see that mice that undergo caloric restriction show a lower

22/09/2025
10/10/2025

We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.

We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies.
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower
We see that mice that undergo caloric restriction show a lower

In the endless journey of life, there is a sacred truth that whispers in the winds of time—one that is felt in the beating of the heart and seen in the winding paths of every living creature. The words of María Blasco Marhuenda offer us a glimpse into this truth: "We see that mice that undergo caloric restriction show a lower telomere shortening rate than those fed with a normal diet. These mice therefore have longer telomeres as adults, as well as lower rates of chromosome anomalies." Ah, how profound these words are, for they speak to the nature of life and longevity, of how the smallest changes, even in the realm of diet, can shape the very essence of our being—transforming the course of our lives in ways we are only beginning to understand.

In the ancient world, great minds such as Hippocrates and Galen understood that the health of the body was intricately tied to the balance of nourishment and moderation. Hippocrates, the father of medicine, often spoke of the importance of balance—of giving the body what it needs without overindulgence. He knew that the body, like a finely tuned instrument, required the right amount of sustenance to remain strong, but not too much, lest it succumb to decay. In the caloric restriction of the mice, we see an echo of this ancient wisdom: that moderation in what we consume is key to maintaining the vitality of the body, even extending the very life of our cells through the preservation of telomeres—those sacred markers that guide our biological journey.

Consider the life of the ancient Spartan warriors, those disciplined men and women who understood that the key to strength lay not in excess but in restraint. They were renowned not for their indulgence, but for their endurance—their ability to live with purpose and moderation, ever-prepared for battle. Their diet was simple, focused on providing the essential nutrients without the luxury of excess. Like the mice in Marhuenda's study, the Spartans knew that caloric restriction—in their case, a controlled intake of food—could sustain them longer, keeping their bodies prepared for the challenges ahead. It was not through indulgence, but through moderation and discipline that they thrived.

In the East, the Buddhists embraced the notion of moderation as part of their spiritual path. Their practice of mindful eating, of restraining desires, was not just about the physical act of consuming food, but about nurturing the soul through balance. The Buddha taught that the path to enlightenment was not through excess but through the quiet discipline of restraint. As Marhuenda’s research shows, it is this restraint—in food, in desires, in the very fabric of our habits—that can protect the body from the ravages of time, extending its life and keeping its essence intact, just as the telomeres of the mice were protected through dietary moderation.

Ah, children of the earth, let us take heed of this wisdom. For we, too, are creatures bound by the same natural laws. The way we nourish our bodies, the choices we make in the food we consume, directly affects the strength of our bodies and the longevity of our lives. Telomeres, those silent markers of our biological age, remind us that time is both a gift and a test. They shorten with age, but they also shorten with excess—with the indulgence of food that is not needed, with the accumulation of things that weigh down the body. But in moderation, in balance, we may preserve our vitality, holding back the hands of time and allowing our bodies to continue in strength.

The lesson is clear, my children: moderation is the key. In your lives, choose to live with intention. Do not overindulge, but rather focus on the sustenance that serves your body and spirit. Just as Hippocrates and the ancient Spartans knew that the body requires nourishment, but not excess, so must you approach your food with care. By practicing caloric restriction, by moderating the quantity of your food, you can preserve the very integrity of your body, extending the fullness of your life.

So, I say to you, children, live with awareness. Embrace the ancient wisdom of moderation in all things. Like the mice in Marhuenda’s study, you too can extend the vitality of your cells and your very lives through mindful choices. Walk the path of balance, and in that balance, you will find the strength to endure, the wisdom to thrive, and the grace to live a long and healthy life.

María Blasco Marhuenda
María Blasco Marhuenda

Spanish - Scientist Born: 1965

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